Products

cDNA Clones

Proteins

Gene Expression

RNAi

Assay Kits

Over-expression Lysates

Recombinant Proteins

CytoSections

Mass Spec Standards

Native Proteins

Mutant Proteins

Mutant CytoSections

Human

Mouse

SARS-CoV-2

Cynomolgus

Rat

Escherichia coli

Rhesus

Bovine

Blomia tropicalis

Chicken

2019-nCoV

Dermatophagoides pteronyssinus

Orf Virus

Rabbit

Staphylococcus aureus

Streptococcus Pyogenes

Hepatitis B Virus

Saccharomyces cerevisiae

Cavia porcellus

Dermatophagoides farinae

HIV

Streptococcus sp.

Alternaria alternata

B.subtilis

Betula pendula

Carassiusauratus

Chlorocebus aethiops

D. aromatica

Drosophila melanogaster

E.coli

Enterobacteria phage T4

Escherichia phage T7

Human herpesvirus

Human papillomavirus

Humon

Humulus japonicus

Klebsiella pneumoniae

Lachnospiraceae bacterium ND2006

Lepidoglyphus destructor

Leptotrichia wadei

Macaca fascicularis

Marmoset

Mucor hiemalis

Mus musculus

Proteobacteria

S. hygroscopicus

SIV

Serratia marcescens

Sheep

Staphylococcus aureus subsp.

Streptococcus

Streptomyces avidinii

Streptomyces plicatus

T. fusca

Tobacco etch virus

Vaccinia virus

Vacciniavirus

Vibrio cholerae

Virus

viral

ALPHA 1 ANTITRYPSIN

BDNF

NCALD

NDRG2

RIBONUCLEASE INHIBITOR

IRF5

UBE2D3

HMGA1

PDE9A

CONSTITUTIVE ANDROSTANE RECEPTOR

MTH1

HNRNP F

TPM1

MBNL1

PQBP1

FGFR1

MYOSIN

14-3-3 ZETA

ALKALINE PHOSPHATASE

FGF1

CATHEPSIN B

MYELIN BASIC PROTEIN

PCBP2

PRKAR1B

TGIF

AURORA A

BIN1

S100 CALCIUM BINDING PROTEIN A13

ALPHA SYNUCLEIN

B3GALT5

CD10

CD59

P38

SULT1A1

ZFYVE27

CAMK2B

FHL1

M-CSF

UBE2I

ICAM2

MAX

ACRV1

ALDOLASE

CPNE1

HNF 4 ALPHA

OSBPL9

TAU

TROPOMYOSIN 3

ANNEXIN A2

GM CSF RECEPTOR ALPHA

MORTALITY FACTOR 4 LIKE 2

NDUF3

NRG1

PAX2

ARSA

ASPARTATE BETA HYDROXYLASE

DGKA

DOUBLECORTIN

DYSTROBREVIN ALPHA

KALLIKREIN 11

PPAR GAMMA

VEGFA

ABLIM2

CARDIAC TROPONIN T

FGL1

FHL2

HNRNPD

IL1RA

JNK1

NEK6

RAB27A

SSH3BP1

TRKB

C2ORF88

C4BPB

CASPASE-7

GIPC

GMPR2

HOMER2

IKK GAMMA

MPST

QK1

RGS3

SEPTIN6

SPART

YPEL5

CD36

COASY

GBA

GLUTAMINE SYNTHETASE

IGF1

IL32

ISOCITRATE DEHYDROGENASE

LMO2

MEIS2

P53

SYNTENIN

THYN1

APC11

CARBONIC ANHYDRASE X

WB

IHC

HEK293T

HEK293

E. coli

Sf9

Insect

CHO

Pichia

Baculovirus

Pichia pastoris

Sf9 insect

human serum

H. vulgare

Human

Other

C-Myc/DDK

C-MYC/DDK

N-His

C-His

Tag Free

N-GST and C-His

C-Fc

C-DDK

C-6His

N-GST and C-HIS

N-GST

C-DDK/His

Myc-DDK

His-tag

C-Fc&His

N-His-ABP (Albumin-Binding Protein)

C-HIS

C-Human Fc

C-mFc

N-His&C-His

C-6His-Avi

N-6His

C-Mouse Fc and 6×His

His-Tag

N-T7&C-His

N-Trx&His

C-8His

C-Mouse Fc

N-His-Trx

C-Fc-Avi

C-hFc

C-6×His

C-Avi-6His

C-Human Fc and 6×His

N-GST, C-His

C-10His

N-Fc

N-His&SUMO

N-GST&His

C-Avi&6His

Tag-free

C- 6×His

hIgG-Tag

C-Fc&AVI

N-Avi

N-HIS

N-His PDCD1(Pro21-Val170)

N-Mouse Fc and C-6×His

C-6xHis

N-His&C-Fc

N-His&T7

N-His-GST

N-His/DDK

N-MARI

N-Trx

C-Fc/His

C-hFc&His

N-8His

hIgG-His-Tag

C-Flag

C-HUMAN

C-Myc-DDK

N-6His-Avi

N-DDK

N-His&Flag

N-His-PDCD1(Pro21-Val170)

N-Human Fc

N-mFc

N-terminal His

N-terminal His-PDCD1(Pro21-Val170) tag

C-6xHis/AVI

C-AVI

C-AVI&His

C-AVI-PLUS

C-Avi

C-Avi-10His

C-Avi-His

C-DDK-His

C-DDK/10xHis

C-DDK/6xHis

C-FC

C-FC-6HIS&C-FC-Flag

C-Fc-Flag&C-Fc-6His

C-Flag,C-6His

C-GST

C-HIS/C

C-HIS/DDK

C-His&AVI

C-His&Flag

C-His&HA&AVI

C-His/DDK

C-Human Fc, Avi

C-Human Fc-Avi

C-hIgG1 Fc

C-hIgG2 Fc

C-hIgG4 Fc

C-hIgG4P Fc

C-mFC

C-mIgG2a Fc

C-mIgG2aFc

C-terminal DDK

C-terminal His

N-10His-Flag

N-6His-FLAG

N-6His-Flag

N-8His&N-FLAG

N-8His-Flag

N-AVI

N-AVI&His

N-Avi&6His

N-DDK/His

N-FC

N-FLAG

N-FUSION

N-Fc-FLAG

N-Flag&C-His

N-Flag&His

N-GFP

N-GST(CKM) and N-His(CKB)

N-Mouse Fc

N-T7

N-TRX

N-TRXA

N-Trx-His

N-hFc

No

Tag free

PE

Yes

MVPro

SDS PAGE

WB

Druggable Genome

Transmembrane

Transcription Factors

Secreted Protein

Protein Kinase

ES Cell Differentiation/IPS

Protease

Stem cell - Pluripotency

Phosphatase

Ion Channels: Other

Adult stem cells

GPCR

Embryonic stem cells

Nuclear Hormone Receptor

P450

Cancer stem cells

Induced pluripotent stem cells

Stem cell relevant signaling - JAK/STAT signaling pathway

Ion Channels: Potassium

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Stem cell relevant signaling - DSL/Notch pathway

Ion Channels: Cys-loop Receptors

ELISA

Ion Channels: Glutamate Receptors

Ion Channels: Transient receptor potential

SDS-PAGE

Ion Channels: ATP Receptors

Bioactivity

Ion Channels: Sodium

10 mM Tris-HCl

the solution can be further dialyzed against PBS (phosphate buffered saline

Flow Cyt

2 mM dithiothreitol

ELISA.
Western Blot.

e.g. Dulbecco's PBS).

Enzyme Activity

Ion Channels: Cyclic nucleotide gated

both dissolved in 9.5 M urea buffer (see above). Protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4 M urea and then to low salt condition (50 mM NaCl

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments is performed by mixing equimolar amounts of keratins of type I and type II at concentrations of approx. 0.5 mg/ml

pH 7.4). For immunization purposes

Ion Channels: Calcium

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments is performed by mixing equimolar amounts of keratins of type I and type II at concentrations of approx. 0.5 mg/ml

pH 7.4).
For immunization purposes

pH 7.4).
For immunization purposes

Western Blot.

0.1% (w/v) insulin

10mM Tris-HCl

1mM DTT

2 mM dithiothreitol

2mM EDTA.
2. Add 4ug of recombinant thioredoxin into reaction cocktail and mix immediately.
3. Incubate at 25°C for 20 minutes.
4. Record the increase in A650nm for 15 minutes

2mM dithiothreitol

63mM sodium phosphate

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments: After vimentin is dissolved in 9.5M Urea buffer (see above)

Can be used as standard in a Sandwich ELISA.

FACS

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments: after desmin is dissolved in 9.5 M urea buffer (see above)

Protocol: Activity Assay
1. Prepare a 1 ml reaction cocktail into a suitable container: The final concentrations are 5mM Tris

Recombinant E. coli derived Human Sonic HedgeHog is a 20.0 kDa protein consisting of 176 amino acid residues

both dissolved in 9.5 M urea buffer (see above).
Protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4 M urea and then to low salt condition (50 mM NaCl

e.g. Dulbeccos PBS).

e.g.Dulbecco's PBS).

including an N-terminal Ile-Val-Ile sequence substituted for the natural occurring chemically modified Cys residue.

protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4M Urea and then to low salt condition (50mM NaCl

protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4M urea and then to low salt condition (50 mM NaCl

the solution can be further dialyzed against PBS (Phosphate Buffered Saline

ELISA.
Suitable for use as a Control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve.
Immunoprecipitation.
Western blotting.

ELISA.
Western Blot.

ELISA.
Western blotting.

ELISA.

Positive control for Western blot analysis

Positive control for Western blot analysis.
Standard for ELISA.

Adermann K. Role of the prosequence of guanylin. Protein Sci. 1999 Sep; 8(9): 1850-9.
4. Lauber T

Cell culture and/or animal studies.
ELISA.
Western Blot.

Cohen MB. Proguanylin secretion and the role of negative-feedback inhibition in a villous epithelial cell line. Am J Physiol Gastrointest Liver Physiol. 2002 Sep; 283(3): G695-702.
3. Schulz A

ELISA.
Western blotting.

For use as a Control or Standard in Indirect trapping ELISA for quantitation of antigen in serum using a standard curve

For use as a Control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve.
Immunoprecipitation.
Western blotting.

Forssmann WG

Hawkins JA

Hidaka Y

Marx UC

Marx UC. Native and recombinant proguanylin feature identical biophysical properties and are monomeric in solution. Biochemistry. 2002 Dec 10; 41(49): 14602-12.
2. Rudolph JA

Marx UC. Solution structure of human proguanylin: the role of a hormone prosequence. J Biol Chem. 2003 Jun 27; 278(26): 24118-24. Epub 2003 Apr 21.

Neudecker P

Nourse A

Rosch P

Schulz A

Shimonishi Y

Specific methodologies have not been tested using this product.

Western Blot.
Protocol: 1. Lauber T

Western Blotting.

for immunoprecipitation and for Wwestern blotting.

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Endocytosis

Chemokine signaling pathway

Jak-STAT signaling pathway

Neurotrophin signaling pathway

Purine metabolism

Natural killer cell mediated cytotoxicity

Ubiquitin mediated proteolysis

Wnt signaling pathway

Alzheimer's disease

Insulin signaling pathway

T cell receptor signaling pathway

Huntington's disease

Cell adhesion molecules (CAMs)

Neuroactive ligand-receptor interaction

Calcium signaling pathway

Axon guidance

Hematopoietic cell lineage

Toll-like receptor signaling pathway

Cell cycle

Leukocyte transendothelial migration

Tight junction

ErbB signaling pathway

Progesterone-mediated oocyte maturation

Oocyte meiosis

Lysosome

Prostate cancer

Apoptosis

GnRH signaling pathway

Pancreatic cancer

Spliceosome

Adherens junction

Colorectal cancer

Fc gamma R-mediated phagocytosis

Systemic lupus erythematosus

Melanoma

Dilated cardiomyopathy

Pyrimidine metabolism

Fc epsilon RI signaling pathway

Hypertrophic cardiomyopathy (HCM)

TGF-beta signaling pathway

Melanogenesis

Parkinson's disease

B cell receptor signaling pathway

Chronic myeloid leukemia

Small cell lung cancer

VEGF signaling pathway

Antigen processing and presentation

Vascular smooth muscle contraction

Renal cell carcinoma

Glioma

RIG-I-like receptor signaling pathway

Oxidative phosphorylation

PPAR signaling pathway

Adipocytokine signaling pathway

Gap junction

NOD-like receptor signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Complement and coagulation cascades

Glycolysis / Gluconeogenesis

p53 signaling pathway

Acute myeloid leukemia

Olfactory transduction

Phosphatidylinositol signaling system

Long-term potentiation

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Pathogenic Escherichia coli infection

Endometrial cancer

Non-small cell lung cancer

Long-term depression

Cytosolic DNA-sensing pathway

Viral myocarditis

ECM-receptor interaction

Bladder cancer

Cardiac muscle contraction

Arginine and proline metabolism

Amyotrophic lateral sclerosis (ALS)

Metabolism of xenobiotics by cytochrome P450

Drug metabolism - cytochrome P450

Glycerophospholipid metabolism

mTOR signaling pathway

Ribosome

Inositol phosphate metabolism

Autoimmune thyroid disease

Vibrio cholerae infection

Amino sugar and nucleotide sugar metabolism

Valine

Glutathione metabolism

Type I diabetes mellitus

Drug metabolism - other enzymes

Thyroid cancer

Type II diabetes mellitus

Retinol metabolism

RNA degradation

leucine and isoleucine degradation

Tyrosine metabolism

Hedgehog signaling pathway

Starch and sucrose metabolism

Proteasome

Pyruvate metabolism

Arachidonic acid metabolism

Graft-versus-host disease

Fructose and mannose metabolism

Fatty acid metabolism

Glycerolipid metabolism

Allograft rejection

Tryptophan metabolism

Alanine

aspartate and glutamate metabolism

Basal cell carcinoma

Nucleotide excision repair

Prion diseases

Cysteine and methionine metabolism

Primary immunodeficiency

Base excision repair

Regulation of autophagy

Androgen and estrogen metabolism

Porphyrin and chlorophyll metabolism

Notch signaling pathway

Lysine degradation

Butanoate metabolism

Sphingolipid metabolism

Pentose phosphate pathway

Nitrogen metabolism

Citrate cycle (TCA cycle)

SNARE interactions in vesicular transport

Propanoate metabolism

Galactose metabolism

DNA replication

Histidine metabolism

Aminoacyl-tRNA biosynthesis

Glycine

serine and threonine metabolism

Asthma

Ether lipid metabolism

Taste transduction

Selenoamino acid metabolism

beta-Alanine metabolism

N-Glycan biosynthesis

Nicotinate and nicotinamide metabolism

Dorso-ventral axis formation

Glycosphingolipid biosynthesis - lacto and neolacto series

Linoleic acid metabolism

Maturity onset diabetes of the young

Phenylalanine metabolism

RNA polymerase

Sulfur metabolism

Basal transcription factors

Glycosaminoglycan degradation

Homologous recombination

Mismatch repair

Pantothenate and CoA biosynthesis

O-Glycan biosynthesis

Pentose and glucuronate interconversions

Renin-angiotensin system

Riboflavin metabolism

Other glycan degradation

Glyoxylate and dicarboxylate metabolism

Ascorbate and aldarate metabolism

Primary bile acid biosynthesis

Terpenoid backbone biosynthesis

One carbon pool by folate

alpha-Linolenic acid metabolism

Heparan sulfate biosynthesis

Biosynthesis of unsaturated fatty acids

Glycosphingolipid biosynthesis - globo series

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Keratan sulfate biosynthesis

C21-Steroid hormone metabolism

Limonene and pinene degradation

Folate biosynthesis

Chondroitin sulfate biosynthesis

Circadian rhythm - mammal

Steroid biosynthesis

Non-homologous end-joining

ABC transporters

leucine and isoleucine biosynthesis

Thiamine metabolism

Taurine and hypotaurine metabolism

Glycosphingolipid biosynthesis - ganglio series

Synthesis and degradation of ketone bodies

Caffeine metabolism

Fatty acid elongation in mitochondria

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Protein export

Cyanoamino acid metabolism

Fatty acid biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Lysine biosynthesis

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

Lipoic acid metabolism

Biotin metabolism

O-Mannosyl glycan biosynthesis

D-Arginine and D-ornithine metabolism

Human

E. coli

Human 293

Plasma

Placenta

Baculovirus

Erythrocytes

Neutrophils

P.Pichia

293F

Brain

CHO Stable

Carcinoma

HEK293

Leukocytes

Mammalian

Pancreas

Pichia pastoris

Pituitary

Synthetic

Urine

1

2

3

Yes

In Stock