cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

P53

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

B RAF

P16INK4A

P21 RAS

EVI1

KRAS

CBL

RAF1

IKK GAMMA

PIK3R5

ACTIVIN A RECEPTOR TYPE IC

MDM2

SHC

NRAS

CTBP2

P21

AKT1

PI 3 KINASE P85 ALPHA

SMAD3

RUNX1

MEK2

PI 3 KINASE P55 GAMMA

ACTIVIN A RECEPTOR TYPE IB

AKT3

MEK1

NF-KB P65

ERK1

STAT5A

A RAF

ERK2

IKK BETA

TGF BETA 2

TGF BETA RECEPTOR II

AKT2

BCL X

C ABL

CDK4

CDK6

GAB2

GRB2

NFKB1

TGF BETA RECEPTOR I

CBLB

P38

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

BAD

BCR

CBL C

CTBP1

P27 KIP 1

E2F3

PIK3CB

RB

SHP2

C-MYC

HDAC2

IKK ALPHA

CRKL

CYCLIN D1

E2F1

HDAC1

IKB ALPHA

PI 3 KINASE P85 BETA

PIK3CD

SHC3

SHC4

SMAD4

SOS1

STAT5B

TGF BETA 1

TGF BETA 3

E2F2

SLI

SOS2

MECOM

TP53

Plasmids

Myc-DDK

mGFP

Tag Free

TurboGFP

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-AC-Myc-DDK

pCMV6-XL5

pCMV6-XL4

pCMV6-AN-Myc-DDK

pCMV6-XL6

pCMV6-AC

No

Yes

TrueORF

LentiORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Transcription Factors

Protein Kinase

Stem cell - Pluripotency

ES Cell Differentiation/IPS

Transmembrane

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - DSL/Notch pathway

Secreted Protein

Cancer stem cells

Phosphatase

Induced pluripotent stem cells

Adult stem cells

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Endocytosis

Chemokine signaling pathway

Calcium signaling pathway

Insulin signaling pathway

Neurotrophin signaling pathway

Ubiquitin mediated proteolysis

Wnt signaling pathway

Olfactory transduction

Colorectal cancer

Huntington's disease

Purine metabolism

Natural killer cell mediated cytotoxicity

Alzheimer's disease

Jak-STAT signaling pathway

Prostate cancer

Progesterone-mediated oocyte maturation

Tight junction

Axon guidance

Cell cycle

Pancreatic cancer

Leukocyte transendothelial migration

T cell receptor signaling pathway

ErbB signaling pathway

Melanoma

Cell adhesion molecules (CAMs)

Oocyte meiosis

Endometrial cancer

Apoptosis

Vascular smooth muscle contraction

B cell receptor signaling pathway

GnRH signaling pathway

Melanogenesis

p53 signaling pathway

Adherens junction

Chronic myeloid leukemia

Toll-like receptor signaling pathway

Lysosome

Fc epsilon RI signaling pathway

Fc gamma R-mediated phagocytosis

Glioma

Small cell lung cancer

Dilated cardiomyopathy

Gap junction

VEGF signaling pathway

Renal cell carcinoma

Non-small cell lung cancer

Hematopoietic cell lineage

mTOR signaling pathway

Hypertrophic cardiomyopathy (HCM)

Spliceosome

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Parkinson's disease

Long-term potentiation

Acute myeloid leukemia

Long-term depression

Oxidative phosphorylation

Type II diabetes mellitus

Systemic lupus erythematosus

Pyrimidine metabolism

Bladder cancer

Thyroid cancer

Adipocytokine signaling pathway

Glycolysis / Gluconeogenesis

TGF-beta signaling pathway

Viral myocarditis

PPAR signaling pathway

Phosphatidylinositol signaling system

Amyotrophic lateral sclerosis (ALS)

Antigen processing and presentation

NOD-like receptor signaling pathway

RIG-I-like receptor signaling pathway

ECM-receptor interaction

Epithelial cell signaling in Helicobacter pylori infection

Basal cell carcinoma

Cardiac muscle contraction

Complement and coagulation cascades

Mismatch repair

Ribosome

Glycerophospholipid metabolism

Amino sugar and nucleotide sugar metabolism

Starch and sucrose metabolism

Primary immunodeficiency

Pathogenic Escherichia coli infection

Vibrio cholerae infection

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Inositol phosphate metabolism

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Arginine and proline metabolism

Notch signaling pathway

RNA degradation

Retinol metabolism

Homologous recombination

Drug metabolism - other enzymes

Glutathione metabolism

Valine

Arachidonic acid metabolism

Galactose metabolism

Maturity onset diabetes of the young

Taste transduction

Nucleotide excision repair

Tyrosine metabolism

N-Glycan biosynthesis

Dorso-ventral axis formation

Autoimmune thyroid disease

Pyruvate metabolism

Lysine degradation

Fatty acid metabolism

leucine and isoleucine degradation

Glycerolipid metabolism

Sphingolipid metabolism

Proteasome

ABC transporters

Prion diseases

Type I diabetes mellitus

Citrate cycle (TCA cycle)

Base excision repair

Cysteine and methionine metabolism

Tryptophan metabolism

Graft-versus-host disease

Fructose and mannose metabolism

SNARE interactions in vesicular transport

Androgen and estrogen metabolism

Porphyrin and chlorophyll metabolism

Alanine

aspartate and glutamate metabolism

Allograft rejection

Ether lipid metabolism

Propanoate metabolism

DNA replication

Aminoacyl-tRNA biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

Glycine

serine and threonine metabolism

Regulation of autophagy

Butanoate metabolism

Histidine metabolism

Pentose phosphate pathway

Basal transcription factors

Nitrogen metabolism

Selenoamino acid metabolism

Glycosaminoglycan degradation

RNA polymerase

Phenylalanine metabolism

Linoleic acid metabolism

O-Glycan biosynthesis

Asthma

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Nicotinate and nicotinamide metabolism

Pentose and glucuronate interconversions

beta-Alanine metabolism

Biosynthesis of unsaturated fatty acids

One carbon pool by folate

Heparan sulfate biosynthesis

Keratan sulfate biosynthesis

Ascorbate and aldarate metabolism

Pantothenate and CoA biosynthesis

Steroid biosynthesis

Primary bile acid biosynthesis

Riboflavin metabolism

Other glycan degradation

Renin-angiotensin system

Chondroitin sulfate biosynthesis

alpha-Linolenic acid metabolism

Non-homologous end-joining

Sulfur metabolism

Terpenoid backbone biosynthesis

Glycosphingolipid biosynthesis - globo series

Glycosphingolipid biosynthesis - ganglio series

Glyoxylate and dicarboxylate metabolism

Circadian rhythm - mammal

Limonene and pinene degradation

Cyanoamino acid metabolism

Taurine and hypotaurine metabolism

leucine and isoleucine biosynthesis

Protein export

Folate biosynthesis

C21-Steroid hormone metabolism

Thiamine metabolism

Caffeine metabolism

Synthesis and degradation of ketone bodies

Fatty acid elongation in mitochondria

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Lipoic acid metabolism

Lysine biosynthesis

O-Mannosyl glycan biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

Neomycin

None

Puromycin

1

Yes

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