XPD (ERCC2) (NM_000400) Human Recombinant Protein

CAT#: TP762657

Purified recombinant protein of Human excision repair cross-complementing rodent repair deficiency, complementation group 2 (ERCC2), transcript variant 1



  View other "XPD" proteins (4)

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CNY 2,480.00


货期*
现货

规格
    • 50 ug

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经常一起买 (1)
ERCC2 mouse monoclonal antibody, clone OTI4B11 (formerly 4B11)
    • 100 ul

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region full length of ERCC2
Tag N-GST and C-HIS
Predicted MW 114.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000391
Locus ID 2068
UniProt ID P18074
Refseq Size 2355
Cytogenetics 19q13.32
Refseq ORF 2280
Synonyms COFS2; EM9; TFIIH; TTD; TTD1; XPD
Summary The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Nucleotide excision repair
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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