Ataxin 3 (ATXN3) (NM_004993) Human Recombinant Protein

CAT#: TP710359

Purified recombinant protein of Human ataxin 3 (ATXN3), transcript variant reference, full length, with with C-terminal DDK tag, expressed in sf9, 20ug



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CNY 4,020.00


货期*
现货

规格
    • 20 ug

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经常一起买 (1)
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Specifications

Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC218923, encoding human full-length ATXN3
Tag C-DDK
Predicted MW 41.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_004984
Locus ID 4287
UniProt ID P54252
Refseq Size 2698
Cytogenetics 14q32.12
Refseq ORF 1083
Synonyms AT3; ATX3; JOS; MJD; MJD1; SCA3
Summary Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016]
Protein Families Druggable Genome, Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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