Ataxin 3 (ATXN3) (NM_004993) Human Mass Spec Standard

CAT#: PH318923

ATXN3 MS Standard C13 and N15-labeled recombinant protein (NP_004984)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description ATXN3 MS Standard C13 and N15-labeled recombinant protein (NP_004984)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218923
Predicted MW 41.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_004984
RefSeq Size 2698
RefSeq ORF 1083
Synonyms AT3; ATX3; JOS; MJD; MJD1; SCA3
Locus ID 4287
Cytogenetics 14q32.12
Summary Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016]
Protein Families Druggable Genome, Transcription Factors
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