Collagen type V Bovine Protein

Specifications

Product Data
Description	Collagen type V bovine protein, 0.5 mg
Species	Bovine
Protein Source	Placenta
Concentration	lot specific
Purity	Prepared from Bovine Placenta and is chromatographically and immunologically pure
Buffer	Presentation State: Purified State: Liquid (sterile filtered) purified Ig fraction Buffer System: 0.5 M Sodium Acetate, pH 4.5 Preservative: 0.01% (w/v) Sodium Azide Stabilizer: None
Preparation	Liquid (sterile filtered) purified Ig fraction
Applications	Suitable for use as a Control or Standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve, for Immunoprecipitation and for other immunological assays optimized by the customer.
Protein Description	This product reacts with anti-Collagen Type V. Reaction with anti-Collagen I, II, III, IV or VI is negligible (typically less than 1% cross reactivity detected by ELISA).
Storage	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Reference Data
RefSeq	NP_000084
Locus ID	1289
Cytogenetics	9q34.3
Synonyms	EDSC; EDSCL1; FMDMF
Summary	This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. The encoded procollagen protein occurs commonly as the heterotrimer pro-alpha1(V)-pro-alpha1(V)-pro-alpha2(V). Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Protein Families	Druggable Genome
Protein Pathways	ECM-receptor interaction, Focal adhesion

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