TBXAS1 (NM_001130966) Human Mass Spec Standard

CAT#: PH325917

TBXAS1 MS Standard C13 and N15-labeled recombinant protein (NP_001124438)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description TBXAS1 MS Standard C13 and N15-labeled recombinant protein (NP_001124438)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225917
Predicted MW 60.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001124438
RefSeq Size 2385
RefSeq ORF 1602
Synonyms BDPLT14; CYP5; CYP5A1; GHOSAL; THAS; TS; TXAS; TXS
Locus ID 6916
Cytogenetics 7q34
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Protein Families Druggable Genome, P450
Protein Pathways Arachidonic acid metabolism, Metabolic pathways
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