ALDH4A1 (NM_003748) Human Mass Spec Standard

CAT#: PH320893

ALDH4A1 MS Standard C13 and N15-labeled recombinant protein (NP_003739)



  View other "ALDH4A1" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description ALDH4A1 MS Standard C13 and N15-labeled recombinant protein (NP_003739)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220893
Predicted MW 61.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_003739
RefSeq Size 3399
RefSeq ORF 1689
Synonyms ALDH4; P5CD; P5CDh
Locus ID 8659
Cytogenetics 1p36.13
Summary This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2009]
Protein Families Druggable Genome
Protein Pathways Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways
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