GTF2IRD1 (NM_005685) Human Mass Spec Standard

CAT#: PH318834

GTF2IRD1 MS Standard C13 and N15-labeled recombinant protein (NP_005676)



  View other "GTF2IRD1" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description GTF2IRD1 MS Standard C13 and N15-labeled recombinant protein (NP_005676)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218834
Predicted MW 104.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_005676
RefSeq Size 3078
RefSeq ORF 2832
Synonyms BEN; CREAM1; GTF3; hMusTRD1alpha1; MUSTRD1; RBAP2; WBS; WBSCR11; WBSCR12
Locus ID 9569
Cytogenetics 7q11.23
Summary The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Basal transcription factors
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