CAMK2A (NM_015981) Human Mass Spec Standard

CAT#: PH318186

CAMK2A MS Standard C13 and N15-labeled recombinant protein (NP_057065)



  View other "CAMK2A" proteins (5)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description CAMK2A MS Standard C13 and N15-labeled recombinant protein (NP_057065)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218186
Predicted MW 55.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_057065
RefSeq Size 4836
RefSeq ORF 1467
Synonyms CAMKA; CaMKIIalpha; CaMKIINalpha; MRD53; MRT63
Locus ID 815
Cytogenetics 5q32
Summary The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018]
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Calcium signaling pathway, ErbB signaling pathway, Glioma, GnRH signaling pathway, Long-term potentiation, Melanogenesis, Neurotrophin signaling pathway, Olfactory transduction, Oocyte meiosis, Wnt signaling pathway
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