Argininosuccinate Lyase (ASL) (NM_000048) Human Mass Spec Standard

CAT#: PH317527

ASL MS Standard C13 and N15-labeled recombinant protein (NP_000039)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

Product images

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Transient overexpression lysate of argininosuccinate lyase (ASL), transcript variant 1
    • 100 ug

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Specifications

Product Data
Description ASL MS Standard C13 and N15-labeled recombinant protein (NP_000039)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217527
Predicted MW 51.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000039
RefSeq Size 1937
RefSeq ORF 1392
Synonyms ASAL
Locus ID 435
Cytogenetics 7q11.21
Summary This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Protein Pathways Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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