MAT1A (NM_000429) Human Mass Spec Standard

CAT#: PH303765

MAT1A MS Standard C13 and N15-labeled recombinant protein (NP_000420)



  View other "MAT1A" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description MAT1A MS Standard C13 and N15-labeled recombinant protein (NP_000420)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203765
Predicted MW 43.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000420
RefSeq Size 3419
RefSeq ORF 1185
Synonyms MAT; MATA1; SAMS; SAMS1
Locus ID 4143
Cytogenetics 10q22.3
Summary This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Cysteine and methionine metabolism, Metabolic pathways, Selenoamino acid metabolism
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