Decorin (DCN) (NM_001920) Human Mass Spec Standard

CAT#: PH302753

DCN MS Standard C13 and N15-labeled recombinant protein (NP_001911)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description DCN MS Standard C13 and N15-labeled recombinant protein (NP_001911)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202753
Predicted MW 39.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001911
RefSeq Size 2305
RefSeq ORF 1077
Synonyms CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B
Locus ID 1634
Cytogenetics 12q21.33
Summary This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways TGF-beta signaling pathway
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