FRA1 (FOSL1) (NM_005438) Human Mass Spec Standard

Specifications

Product Data
Description	FOSL1 MS Standard C13 and N15-labeled recombinant protein (NP_005429)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202104
Predicted MW	29.4 kDa
Protein Sequence	Sequence Link (showhide) >RC202104 representing NM_005438 Red=Cloning site Green=Tags(s) MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLGPSSYPRPLTY PQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKL EDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKEGDTGSTSGTSSPPAPCRPVPCISLSPGPVL EPEALHTPTLMTTPSLTPFTPSLVFTYPSTPEPCASAHRKSSSSSGDPSSDPLGSPTLLAL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005429
RefSeq Size	1759
RefSeq ORF	813
Synonyms	FRA; fra-1; FRA1
Locus ID	8061
Cytogenetics	11q13.1
Summary	The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Wnt signaling pathway

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