STK16 (NM_003691) Human Mass Spec Standard

Specifications

Product Data
Description	STK16 MS Standard C13 and N15-labeled recombinant protein (NP_003682)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200566
Predicted MW	34.7 kDa
Protein Sequence	Sequence Link (showhide) >RC200566 protein sequence Red=Cloning site Green=Tags(s) MGHALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHR LFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIH AKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHC VIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIPQSPRHSSALWQLLNSMMTVDPHQR PHIPLLLSQLEALQPPAPGQHTTQI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003682
RefSeq Size	1682
RefSeq ORF	915
Synonyms	FLJ39635; KRCT; KRCT, MPSK, TSF1, PKL12, FLJ39635; MPSK; PKL12; protein kinase expressed in day 12 fetal liver; serine/threonine kinase 16; TSF1
Locus ID	8576
Cytogenetics	2q35
Summary	Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome, Protein Kinase

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