United States
Germany
Japan
United Kingdom
China
Mad2l2 (NM_001012106) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR210119L4V
- LentiORF®
-
Lenti ORF particles, Mad2l2 (GFP-tagged ORF) - Rat MAD2 mitotic arrest deficient-like 2 (yeast) (Mad2l2), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,360.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Mad2l2 (NM_001012106) Rat Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001012106 |
| ORF Size | 702 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR210119).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001012106.1, NP_001012106.1 |
| RefSeq Size | 1188 bp |
| RefSeq ORF | 705 bp |
| Locus ID | 313702 |
| Gene Summary | Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection. Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
