United States
Germany
Japan
United Kingdom
China
ICAD (DFFA) (NM_213566) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC220837L4V
- LentiORF®
-
Lenti ORF particles, DFFA (mGFP-tagged) - Human DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 2, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 9,120.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Product Name | ICAD (DFFA) (NM_213566) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | DFF-45; DFF1; ICAD |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_213566 |
| ORF Size | 804 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC220837).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_213566.1 |
| RefSeq Size | 3408 bp |
| RefSeq ORF | 807 bp |
| Locus ID | 1676 |
| Protein Pathways | Apoptosis |
| MW | 29.2 kDa |
| Gene Summary | Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
