United States
Germany
Japan
United Kingdom
China
Adenylosuccinate Lyase (ADSL) (NM_000026) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC200524L3V
- LentiORF®
-
Lenti ORF particles, ADSL (Myc-DDK tagged) - Human adenylosuccinate lyase (ADSL), transcript variant 1, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,930.00
Product images
CNY 1,999.00
CNY 2,700.00
CNY 2,950.00
Specifications
| Product Data | |
| Product Name | Adenylosuccinate Lyase (ADSL) (NM_000026) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | AMPS; ASASE; ASL |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_000026 |
| ORF Size | 1452 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC200524).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000026.1 |
| RefSeq Size | 1565 bp |
| RefSeq ORF | 1455 bp |
| Locus ID | 158 |
| Domains | lyase_1 |
| Protein Families | Druggable Genome |
| Protein Pathways | Alanine, aspartate and glutamate metabolism, Metabolic pathways, Purine metabolism |
| MW | 54.9 kDa |
| Gene Summary | The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015] |
Documents
| Product Manuals |
| FAQs |
| SDS |
