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Inpp5f (NM_178641) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR224434L3V
- LentiORF®
-
Lenti ORF particles, Inpp5f (Myc-DDK-tagged) - Mouse inositol polyphosphate-5-phosphatase F (Inpp5f), 200ul, >10^7 TU/mL
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CNY 16,720.00
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Specifications
| Product Data | |
| Product Name | Inpp5f (NM_178641) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 5830435P03Rik; AI115354; AW561896; cI-27; hSAC2; mKIAA0966; SAC2 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_178641 |
| ORF Size | 3399 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR224434).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_178641.5, NP_848756.2 |
| RefSeq Size | 4740 bp |
| RefSeq ORF | 3399 bp |
| Locus ID | 101490 |
| Gene Summary | Inositol 4-phosphatase which mainly acts on phosphatidylinositol 4-phosphate. May be functionally linked to OCRL, which converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol, for a sequential dephosphorylation of phosphatidylinositol 4,5-bisphosphate at the 5 and 4 position of inositol, thus playing an important role in the endocytic recycling (PubMed:25869668, PubMed:25869669). Regulator of TF:TFRC and integrins recycling pathway, is also involved in cell migration mechanisms (By similarity). Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (PubMed:17322895). Negatively regulates STAT3 signaling pathway through inhibition of STAT3 phosphorylation and translocation to the nucleus (By similarity). Functionally important modulator of cardiac myocyte size and of the cardiac response to stress (PubMed:19875726). May play a role as negative regulator of axon regeneration after central nervous system injuries (PubMed:26203138).[UniProtKB/Swiss-Prot Function] |
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