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SGT1 (ECD) (NM_007265) Human Untagged Clone
CAT＃: SC321385
ECD (untagged)-Human ecdysoneless homolog (Drosophila) (ECD), transcript variant 1
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GCR2; HSGT1; SGT1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_007265.1
CAAGGTTTCGGGGACTGAGTGGGTTTCAGACTTTCTCTCAGGATTTCCGCTGGCTTCAGG
TTCCGGTCAGGCGTCGGGACAGAGCCTGATCCAGGCTTCGGCGGCCGGTGGCAGCTCTCG ATCAGCTCTCGCAGTCGGAGAGGCGGCTAAGGAAAGGTGCCACAGCAGAGACGCGAAGGA GAGGCCCTAGAACCTTTTCAAAGAAGAATGGAAGAAACCATGAAGCTTGCTACGATGGAA GACACAGTGGAGTACTGCCTGTTCCTGATACCAGATGAGTCAAGGGACTCAGATAAACAT AAAGAGATTCTTCAGAAGTACATTGAGAGAATAATCACTCGGTTTGCACCTATGCTGGTC CCCTACATCTGGCAGAATCAGCCTTTCAATCTTAAATATAAACCTGGGAAAGGAGGTGTT CCTGCTCATATGTTTGGCGTGACAAAGTTTGGGGATAACATTGAGGATGAATGGTTTATT GTTTATGTAATAAAGCAGATCACAAAGGAATTTCCAGAGTTAGTAGCAAGGATTGAAGAC AATGATGGTGAATTCTTGTTAATAGAAGCTGCTGACTTTCTCCCTAAATGGCTGGATCCT GAAAATAGCACCAATAGGGTATTTTTCTGCCATGGGGAATTGTGTATTATCCCTGCACCA AGAAAATCTGGAGCAGAATCTTGGTTACCCACCACACCCCCAACAATTCCACAAGCATTG AATATAATCACAGCACATTCAGAAAAAATACTTGCTTCAGAATCTATACGAGCTGCTGTG AATAGGCGCATCAGAGGGTACCCAGAAAAAATTCAGGCCTCACTTCATCGAGCACACTGC TTCCTTCCAGCTGGCATTGTGGCAGTGCTAAAGCAGCGCCCCAGATTGGTGGCTGCAGCA GTCCAGGCATTTTACCTACGAGACCCTATTGACCTGCGAGCTTGTCGTGTTTTCAAGACA TTCTTGCCTGAAACACGAATAATGACATCGGTCACATTCACTAAATGTCTATATGCACAA TTGGTGCAACAAAGGTTTGTGCCAGACCGGCGGAGTGGATACAGGCTGCCTCCTCCATCT GATCCCCAGTACCGAGCCCATGAATTGGGCATGAAATTGGCTCATGGATTTGAGATCTTA TGCTCCAAATGTAGCCCACATTTTTCTGACTGCAAGAAATCCCTTGTGACTGCCTCACCA CTCTGGGCCAGTTTCCTTGAAAGTCTGAAAAAGAATGATTACTTTAAGGGACTGATAGAA GGTTCTGCTCAGTACCGGGAAAGGCTAGAAATGGCAGAGAATTACTTCCAGCTCTCAGTA GACTGGCCAGAAAGTTCTCTTGCTATGAGCCCTGGTGAAGAAATCTTAACCTTATTACAG ACAATACCATTTGATATAGAAGACCTTAAGAAAGAAGCAGCTAATCTTCCCCCAGAGGAT GATGACCAGTGGTTAGATCTCTCACCAGATCAGCTGGACCAGCTGCTGCAGGAAGCTGTT GGCAAAAAAGAATCCGAGTCTGTTTCCAAGGAGGAGAAGGAGCAGAACTATGACTTAACT GAAGTCTCAGAGAGCATGAAAGCTTTCATATCCAAAGTCTCAACCCACAAGGGAGCAGAG CTGCCTCGAGAACCTTCTGAGGCTCCAATCACTTTTGATGCAGATTCTTTTCTTAATTAT TTTGATAAGATTTTAGGGCCAAGGCCTAATGAGTCAGATTCTGATGATCTGGATGATGAA GACTTTGAATGTTTAGATAGTGATGATGACTTGGACTTTGAAACACACGAACCTGGCGAA GAGGCTTCCCTGAAAGGAACACTTGATAATCTCAAGTCATACATGGCCCAGATGGACCAG GAACTAGCACACACCTGCATCAGCAAAAGTTTCACCACTAGGAACCAAGTGGAACCTGTA TCCCAGACTACCGATAACAATTCAGATGAGGAAGATTCTGGTACGGGAGAATCTGTTATG GCACCAGTAGATGTAGACCTGAACCTGGTTTCAAATATATTGGAATCCTATAGCTCCCAA GCTGGACTGGCAGGACCTGCTTCCAATCTTTTACAAAGCATGGGAGTGCAGCTGCCTGAC AACACCGATCACAGACCAACAAGTAAGCCAACAAAAAATTAACCAGCACATTTAGCTTCT CTTTTTTCTTTTTAAATAAATATTGAATATGAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_007265 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007265.1, NP_009196.1 |
| RefSeq Size | 2200 bp |
| RefSeq ORF | 1935 bp |
| Locus ID | 11319 |
| UniProt ID | O95905 |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP (PubMed:16849563, PubMed:23880345). May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes (PubMed:19919181, PubMed:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins (PubMed:19640839). The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex (PubMed:26711270). May play a role in regulation of pre-mRNA splicing (PubMed:24722212).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents a more abundant transcript and encodes isoform 1. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200384 | ECD (Myc-DDK-tagged)-Human ecdysoneless homolog (Drosophila) (ECD), transcript variant 1 |
CNY 4,792.00 |
|
| RC200384L3 | Lenti ORF clone of Human ecdysoneless homolog (Drosophila) (ECD), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200384L4 | Lenti ORF clone of Human ecdysoneless homolog (Drosophila) (ECD), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG200384 | ECD (tGFP-tagged) - Human ecdysoneless homolog (Drosophila) (ECD), transcript variant 1 |
CNY 4,370.00 |
