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PDE6D (NM_002601) Human Untagged Clone
CAT＃: SC118535
PDE6D (untagged)-Human phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D)
CNY 1,800.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | JBTS22; PDED |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_002601 edited
ATGTCAGCCAAGGACGAGCGGGCCAGGGAGATCCTGAGGGGCTTCAAACTAAATTGGATG AACCTTCGGGATGCTGAGACAGGGAAGATACTCTGGCAAGGAACAGAAGACCTGTCTGTC CCTGGTGTGGAGCATGAAGCCCGTGTTCCCAAGAAAATCCTCAAGTGCAAGGCAGTGTCT CGAGAACTTAATTTTTCTTCGACAGAACAAATGGAAAAATTCCGCCTGGAACAAAAAGTT TACTTCAAAGGGCAATGCCTAGAAGAATGGTTCTTCGAGTTTGGCTTTGTGATCCCTAAC TCCACAAATACCTGGCAGTCCTTGATAGAGGCAGCACCCGAGTCCCAGATGATGCCAGCA AGCGTCTTAACTGGGAACGTTATCATAGAAACAAAGTTTTTTGACGACGATCTTCTTGTA AGCACATCCAGAGTGAGACTTTTCTATGTTTGA >OriGene 5' read for NM_002601 unedited
TTTGTACTACGAACTCACTATAGGGCGGCCGCGACATTCGCACGAGGGAGAGAGAGGCCG GTCCTGGTCTGGCCGCTGCGGCTGCTAGCCCGAGGTCTCCAAGCCGGGCTGCGGCTCCAT CCTCGGCTCCTGGGCACCGTCTGCGAGGCTCCGCCGACCAGAGTGAGAAAGCCGCGGGCG GCGACCGCCGCATCATGTCAGCCAAGGACGAGCGGGCCAGGGAGATCCTGAGGGGCTTCA AACTAAATTGGATGAACCTTCGGGATGCTGAGACAGGGAAGATACTCTGGCAAGGAACAG AAGACCTGTCTGTCCCTGGTGTGGAGCATGAAGCCCGTGTTCCCAAGAAAATCCTCAAGT GCAAGGCAGTGTCTCGAGAACTTAATTTTTCTTCGACAGAACAAATGGAAAAATTCCGCC TGGAACAAAAAGTTTACTTCAAAGGGCAATGCCTAGAAGAATGGTTCTTCGAGTTTGGCT TTGTGATCCCTAACTCCACAAATACCTGGCAGTCCTTGATAGAGGCAGCACCCGAGTCCC AGATGATGCCAGCAAGCGTCTTAACTGGGAACGTTATCATAGAAACAAAGTTTTTTGACG ACGATCTTCTTGTAAGCACATCCAGAGTGAGACTTTTCTATGTTTGAAAGAAGAATGTGT GTACATTTCAAGAATTTGGGTTTTTTGGAGGGAGGAGGAAACTGTTTACTTTTTTCCTNC ACACGTTTGATTTTNGACACATACACCCCTAATTCCCTCACAGCAGAACCTACCTGCAGC CACCANGGGACCAGCTCTGTGTAGGTACCAGATGGCTCTTTTCCAGCCGNCATCTTCAGC TGACAGACTAACTNCCAACCCAGACAGGCAGGGGAACAGTTTAAGTCCTTCCANCTACCA CGGAACAAAACATACACAACGGTACTGACCT >OriGene 3' read for NM_002601 unedited
GGACGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAA TTCATATTTTTAATTACATTATGTAATAATATCACAGTCTATTTTACAAGTTAAATGTAT GAAAATGTATGAAATAAAAATGGTAGGAAAAAACTAAACATGGGTCAGGAACACGGAATT TTTCCAAAACCAGGGGCCAAAGGTAAATGTGTAGCCTGTAGGGCCCAAGGAGGAAACAAG GAGGGTGACAGGTACAGTTACCGGTTTGGGGTATGTGTTTGTTCCCTGTGTGTATGCTGG GAAGGACTTGAAACCTGTCCCCTGCCCTGGTCTGGGGTTGGGAGTTTAGTCTGGTCAGCT GGAAAATGGCGGCTTGGGAAAAAGAGCCATCTGGTTACCTACACAGAGCTGGTCCCCTGG TGGCTGCAGGTAGGTTCTGCTGTTGAGGGAATTAGGGGTGTATGTGTCAAAAATCAAACG TGTGGAGGAAAAAAGTAAACAGTTTCCTCCTCCCTCCAAAAAACCCAAATTCTTGAAATG TACACACATTCTTCTTTCAAACATAGAAAAGTCTCACTCTGGATGTGCTTACAAGAAGAT CGTCGTCAAAAAACTTTGTTTCTATGATAACGTTCCCAGGTAAGACGCTTGCTGGCATCA TCTGGGACCTCGGTGCTGCCTCTTCAAGGACTGCCAGTTTTTTGTGGATTAGGGATTCCA AACCCAACTTCAAGACCCTTTTTCTAGGCATTGCCCTTTAAATAAACTTTTTGTCCAGGC GGAATTTTTCTTTTGTTTTGTCAAAAAAAATAATTCTCAAAAACTGCCTGCCTTGAGGAT TTTTTGGAACCCGGCTTATGCTTCCCACAGGGAGACAGGGTTTTGTCTTTTCCAAATTTT TTCTCGTTAATCCCAAAGT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002601 |
| Insert Size | 1070 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002601.2, NP_002592.1 |
| RefSeq Size | 1140 bp |
| RefSeq ORF | 453 bp |
| Locus ID | 5147 |
| UniProt ID | O43924 |
| Protein Pathways | Progesterone-mediated oocyte maturation, Purine metabolism |
| Gene Summary | This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants. [provided by RefSeq, Mar 2014] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203172 | PDE6D (Myc-DDK-tagged)-Human phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D) |
CNY 1,800.00 |
|
| RC203172L1 | Lenti ORF clone of Human phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D), Myc-DDK-tagged |
CNY 4,200.00 |
|
| RC203172L2 | Lenti ORF clone of Human phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D), mGFP tagged |
CNY 5,890.00 |
|
| RC203172L3 | Lenti ORF clone of Human phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203172L4 | Lenti ORF clone of Human phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D), mGFP tagged |
CNY 4,200.00 |
|
| RG203172 | PDE6D (tGFP-tagged) - Human phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D) |
CNY 3,400.00 |
