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Plexin A1 (PLXNA1) (NM_032242) Human Tagged ORF Clone
CAT＃: RC222057
PLXNA1 (Myc-DDK-tagged)-Human plexin A1 (PLXNA1)
ORF Plasmid: tGFP
"NM_032242" in other vectors (3)
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CNY 19,112.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | NOV; NOVP; PLEXIN-A1; PLXN1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC222057 representing NM_032242
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCGCTGCCACCGCGGAGCCTGCAGGTGCTCCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGCCGGGCA TGTGGGCTGAGGCAGGCTTGCCCAGGGCAGGCGGGGGTTCACAGCCCCCCTTCCGCACCTTCTCGGCCAG CGACTGGGGCCTCACCCACCTAGTGGTGCATGAGCAGACAGGCGAGGTGTATGTGGGCGCAGTGAACCGC ATCTATAAGCTGTCGGGGAACCTGACACTGCTGCGGGCCCACGTCACGGGCCCTGTGGAGGACAACGAGA AGTGCTACCCGCCGCCCAGCGTGCAGTCCTGCCCCCACGGCCTGGGCAGTACTGACAACGTCAACAAGCT GCTGCTGCTGGACTATGCCGCTAACCGCCTGCTGGCCTGTGGCAGCGCCTCCCAGGGCATCTGCCAGTTC CTGCGTCTGGACGATCTCTTCAAACTGGGTGAGCCACACCACCGTAAGGAGCACTACCTGTCCAGCGTGC AGGAGGCAGGCAGCATGGCGGGCGTGCTCATTGCCGGGCCACCGGGCCAGGGCCAGGCCAAGCTCTTCGT GGGCACACCCATCGATGGCAAGTCCGAGTACTTCCCCACACTGTCCAGCCGTCGGCTCATGGCCAACGAG GAGGATGCCGACATGTTCGGCTTCGTGTACCAGGATGAGTTTGTGTCATCACAGCTCAAGATCCCTTCGG ACACGCTGTCCAAGTTCCCGGCCTTTGACATCTACTATGTGTACAGCTTCCGCAGCGAGCAGTTTGTCTA CTACCTCACGCTGCAGCTAGACACACAGCTGACCTCGCCTGATGCCGCCGGCGAGCACTTCTTCACGTCC AAGATCGTGCGGCTCTGTGTGGACGACCCCAAATTCTACTCGTACGTTGAGTTCCCCATTGGCTGCGAGC AGGCGGGTGTGGAGTACCGCCTGGTGCAGGATGCCTACCTGAGCCGGCCCGGCCGTGCCCTGGCCCACCA GCTGGGCCTGGCTGAGGACGAGGACGTGCTGTTCACTGTGTTCGCCCAGGGCCAGAAGAACCGCGTGAAG CCACCAAAGGAGTCAGCACTGTGCCTGTTCACGCTCAGGGCCATCAAGGAGAAGATTAAGGAGCGCATCC AGTCCTGCTACCGTGGTGAGGGCAAGCTCTCCCTGCCGTGGCTGCTCAACAAGGAGCTGGGCTGCATCAA CTCGCCCCTGCAGATCGATGACGACTTCTGCGGGCAGGACTTCAACCAGCCCCTGGGGGGCACAGTCACC ATTGAGGGGACGCCCCTGTTCGTGGACAAGGATGATGGCCTGACCGCCGTGGCTGCCTATGACTATCGGG GCCGCACTGTGGTATTCGCCGGCACGCGAAGTGGCCGCATCCGCAAGATCCTGGTGGACCTCTCAAACCC CGGTGGCCGGCCTGCCCTGGCCTACGAGAGCGTCGTGGCCCAGGAGGGCAGCCCCATCCTGCGAGACCTC GTCCTCAGCCCCAACCACCAGTACCTCTACGCCATGACCGAGAAGCAGGTGACGCGGGTGCCTGTGGAGA GCTGTGTGCAGTACACGTCCTGTGAGCTGTGTCTGGGGTCACGGGACCCCCACTGTGGCTGGTGTGTCCT GCACAGCATCTGCTCGCGGCGGGACGCCTGTGAGCGAGCAGACGAGCCCCAGCGCTTTGCTGCGGACCTG CTGCAGTGTGTGCAGCTGACTGTGCAGCCCCGCAATGTGTCTGTCACCATGTCCCAGGTCCCACTTGTGC TGCAGGCCTGGAACGTGCCTGACCTCTCAGCTGGCGTCAACTGCTCCTTCGAGGACTTCACGGAATCTGA GAGCGTCCTGGAGGATGGCCGGATCCACTGCCGCTCACCCTCCGCCCGGGAGGTGGCGCCCATCACGCGG GGCCAGGGAGACCAGCGGGTGGTGAAACTCTACCTAAAGTCCAAGGAGACAGGGAAGAAGTTTGCGTCTG TGGACTTCGTCTTCTACAACTGCAGCGTCCACCAGTCCTGCCTGTCCTGTGTCAACGGCTCCTTTCCCTG CCACTGGTGCAAATACCGCCACGTGTGCACACACAACGTGGCTGACTGCGCCTTCCTGGAGGGCCGTGTC AACGTGTCTGAGGACTGCCCACAGATCCTGCCCTCCACGCAGATCTACGTGCCAGTGGGAGTGGTAAAAC CCATCACCCTGGCCGCACGGAACCTGCCACAGCCACAGTCAGGCCAGCGTGGATATGAGTGCCTCTTCCA CATCCCGGGCAGCCCGGCCCGTGTCACCGCCCTGCGCTTCAACAGCTCCAGCCTGCAGTGCCAGAATTCC TCGTACTCCTACGAGGGGAACGATGTCAGCGACCTGCCAGTGAACCTGTCAGTCGTGTGGAACGGCAACT TTGTCATTGACAACCCACAGAACATCCAGGCGCACCTCTACAAGTGCCCGGCCCTGCGCGAGAGCTGCGG CCTCTGCCTCAAGGCCGACCCGCGCTTCGAGTGCGGATGGTGCGTGGCCGAGCGCCGCTGCTCCCTGCGA CACCACTGCGCTGCCGACACACCTGCATCGTGGATGCACGCGCGTCACGGCAGCAGTCGCTGCACCGACC CCAAGATCCTCAAGCTGTCCCCCGAGACGGGCCCGAGGCAGGGCGGCACGCGGCTCACTATCACAGGCGA GAACCTGGGCCTGCGATTCGAAGACGTGCGTCTGGGCGTGCGCGTGGGCAAGGTGCTGTGCAGCCCTGTG GAGAGCGAGTACATCAGTGCGGAGCAGATCGTCTGTGAGATCGGGGACGCCAGCTCCGTGCGTGCCCATG ACGCCCTGGTGGAGGTGTGTGTGCGGGACTGCTCACCACACTACCGCGCCCTGTCACCCAAGCGCTTCAC CTTCGTGACACCAACCTTCTACCGTGTGAGCCCCTCCCGTGGGCCTCTGTCAGGGGGCACCTGGATTGGC ATCGAGGGAAGCCACCTGAACGCAGGCAGTGATGTGGCTGTGTCGGTCGGTGGCCGGCCCTGCTCCTTCT CCTGGAGGAACTCCCGTGAGATCCGGTGCCTGACACCCCCCGGGCAGAGCCCTGGCAGCGCTCCCATCAT CATCAACATCAACCGCGCCCAGCTCACCAACCCTGAGGTGAAGTACAACTACACCGAGGACCCCACCATC CTGAGGATCGACCCCGAGTGGAGCATCAACAGCGGTGGGACCCTCCTGACGGTCACAGGCACCAACCTGG CCACTGTCCGTGAACCCCGAATCCGGGCCAAGTATGGAGGCATTGAGAGGGAGAACGGCTGCCTGGTGTA CAATGACACCACCATGGTATGCCGCGCCCCGTCTGTGGCCAACCCTGTGCGCAGCCCACCAGAGCTGGGG GAGCGGCCGGATGAGCTGGGCTTCGTCATGGACAACGTGCGCTCCCTGCTTGTGCTCAACTCCACCTCCT TCCTCTACTACCCTGACCCCGTACTGGAGCCACTCAGCCCCACTGGCCTGCTGGAGCTGAAGCCCAGCTC CCCACTCATCCTCAAGGGCCGGAACCTCTTGCCACCTGCACCCGGCAACTCCCGACTCAACTACACGGTG CTCATCGGCTCCACACCCTGTACCCTCACCGTGTCGGAGACGCAACTGCTGTGCGAGGCGCCCAACCTCA CTGGGCAGCACAAGGTCACGGTGCGGGCAGGTGGCTTCGAGTTCTCGCCAGGGACACTGCAGGTGTACTC GGACAGCCTGCTGACGCTGCCTGCCATTGTGGGCATTGGCGGAGGCGGGGGTCTCCTGCTGCTGGTCATC GTGGCTGTGCTCATCGCCTACAAGCGCAAGTCACGAGATGCTGACCGCACACTCAAGCGGCTGCAGCTCC AGATGGACAACCTGGAGTCCCGCGTGGCCCTCGAATGCAAGGAAGCCTTTGCAGAGCTGCAGACAGACAT CCACGAGCTGACCAATGACCTGGACGGTGCCGGCATCCCCTTCCTTGACTACCGGACATATGCCATGCGG GTGCTCTTTCCTGGGATCGAGGACCACCCTGTGCTCAAGGAGATGGAGGTGCAGGCCAATGTGGAGAAGT CGCTGACACTGTTCGGGCAGCTGCTGACCAAGAAGCACTTCCTGCTGACCTTCATCCGCACGCTGGAGGC ACAGCGCAGCTTCTCCATGCGCGACCGCGGGAATGTGGCCTCGCTCATCATGACGGCCCTGCAGGGCGAG ATGGAATACGCCACAGGCGTGCTCAAGCAGCTGCTTTCCGACCTCATCGAGAAGAACCTGGAGAGCAAGA ACCACCCCAAGCTGCTACTGCGCCGGACTGAGTCGGTGGCAGAGAAGATGCTAACTAACTGGTTCACCTT CCTCTTGTATAAGTTCCTCAAGGAGTGCGCTGGGGAGCCGCTGTTCATGCTGTACTGCGCCATCAAGCAG CAGATGGAGAAGGGCCCCATTGACGCCATCACGGGTGAGGCACGCTACTCCCTGAGTGAGGACAAGCTCA TCCGGCAGCAGATTGACTACAAGACACTGACCCTGAACTGTGTGAACCCTGAGAATGAGAATGCACCTGA GGTGCCGGTGAAGGGGCTGGACTGTGACACGGTCACCCAGGCCAAGGAGAAGCTGCTGGACGCTGCCTAC AAGGGCGTGCCCTACTCCCAGCGGCCCAAGGCCGCGGACATGGACCTGGAGTGGCGCCAGGGCCGCATGG CGCGCATCATCCTGCAGGACGAGGACGTCACCACCAAGATTGACAACGATTGGAAGAGGCTGAACACACT GGCTCACTACCAGGTGACAGACGGGTCCTCGGTGGCACTGGTGCCCAAGCAGACGTCCGCCTACAACATC TCCAACTCCTCCACCTTCACCAAGTCCCTCAGCAGATACGAGAGCATGCTGCGCACGGCCAGCAGCCCCG ACAGCCTGCGCTCGCGCACGCCCATGATCACGCCCGACCTGGAGAGCGGCACCAAGCTGTGGCACCTGGT GAAGAACCACGACCACCTGGACCAGCGTGAGGGTGACCGCGGCAGCAAGATGGTCTCGGAGATCTACTTG ACACGGCTACTGGCCACCAAGGGCACACTGCAGAAGTTTGTGGACGACCTGTTTGAGACCATCTTCAGCA CGGCACACCGGGGCTCAGCCCTGCCGCTGGCCATCAAGTACATGTTCGACTTCCTGGATGAGCAGGCCGA CAAGCACCAGATCCACGATGCTGACGTGCGCCACACCTGGAAGAGCAACTGCCTGCCCCTGCGCTTCTGG GTGAACGTGATCAAGAACCCACAGTTTGTGTTCGACATTCACAAGAACAGCATCACGGACGCCTGCTTGT CGGTGGTGGCCCAGACCTTCATGGACTCCTGCTCCACCTCTGAGCACAAGCTGGGCAAGGACTCACCCTC CAACAAGCTGCTCTACGCCAAGGACATCCCCAACTACAAGAGCTGGGTGGAGAGGTACTATGCAGACATC GCCAAGATGCCAGCCATCAGCGACCAGGACATGAGTGCGTATCTGGCTGAGCAGTCCCGCCTGCACCTGA GCCAGTTCAACAGCATGAGCGCCTTGCACGAGATCTACTCCTACATCACCAAGTACAAGGATGAGATCCT GGCAGCCCTGGAGAAGGATGAGCAGGCGCGGCGGCAGCGGCTGCGGAGCAAGCTGGAGCAGGTGGTGGAC ACGATGGCCCTGAGCAGC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC222057 representing NM_032242
Red=Cloning site Green=Tags(s) MPLPPRSLQVLLLLLLLLLLLPGMWAEAGLPRAGGGSQPPFRTFSASDWGLTHLVVHEQTGEVYVGAVNR IYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQF LRLDDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANE EDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTS KIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRVK PPKESALCLFTLRAIKEKIKERIQSCYRGEGKLSLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVT IEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDL VLSPNHQYLYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAADL LQCVQLTVQPRNVSVTMSQVPLVLQAWNVPDLSAGVNCSFEDFTESESVLEDGRIHCRSPSAREVAPITR GQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQSCLSCVNGSFPCHWCKYRHVCTHNVADCAFLEGRV NVSEDCPQILPSTQIYVPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTALRFNSSSLQCQNS SYSYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECGWCVAERRCSLR HHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLCSPV ESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWIG IEGSHLNAGSDVAVSVGGRPCSFSWRNSREIRCLTPPGQSPGSAPIIININRAQLTNPEVKYNYTEDPTI LRIDPEWSINSGGTLLTVTGTNLATVREPRIRAKYGGIERENGCLVYNDTTMVCRAPSVANPVRSPPELG ERPDELGFVMDNVRSLLVLNSTSFLYYPDPVLEPLSPTGLLELKPSSPLILKGRNLLPPAPGNSRLNYTV LIGSTPCTLTVSETQLLCEAPNLTGQHKVTVRAGGFEFSPGTLQVYSDSLLTLPAIVGIGGGGGLLLLVI VAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDGAGIPFLDYRTYAMR VLFPGIEDHPVLKEMEVQANVEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRGNVASLIMTALQGE MEYATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFMLYCAIKQ QMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNCVNPENENAPEVPVKGLDCDTVTQAKEKLLDAAY KGVPYSQRPKAADMDLEWRQGRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYNI SNSSTFTKSLSRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDHLDQREGDRGSKMVSEIYL TRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHQIHDADVRHTWKSNCLPLRFW VNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADI AKMPAISDQDMSAYLAEQSRLHLSQFNSMSALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQVVD TMALSS TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_032242 |
| ORF Size | 5688 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_032242.3, NP_115618.3 |
| RefSeq Size | 9071 bp |
| RefSeq ORF | 5691 bp |
| Locus ID | 5361 |
| UniProt ID | Q9UIW2 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Axon guidance |
| MW | 211.1 kDa |
| Gene Summary | Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance
,null,
Cell
,PubMed ID 30661757
[Plexin A1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222057L1 | Lenti ORF clone of Human plexin A1 (PLXNA1), Myc-DDK-tagged |
CNY 21,512.00 |
|
| RG222057 | PLXNA1 (tGFP-tagged) - Human plexin A1 (PLXNA1) |
CNY 20,712.00 |
|
| SC309736 | PLXNA1 (untagged)-Human plexin A1 (PLXNA1) |
CNY 13,856.00 |
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