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Retinoid X Receptor gamma (RXRG) (NM_006917) Human Tagged ORF Clone
CAT＃: RC204093
RXRG (Myc-DDK-tagged)-Human retinoid X receptor, gamma (RXRG), transcript variant 1
ORF Plasmid: tGFP
"NM_006917" in other vectors (6)
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CNY 3,656.00
CNY 3,990.00
| Cited in 4 publications. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | NR2B3; RXRC |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC204093 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTATGGAAATTATTCTCACTTCATGAAGTTTCCCGCAGGCTATGGAGGCTCCCCTGGCCACACTGGCT CTACATCCATGAGCCCATCAGCAGCCTTGTCCACAGGGAAGCCAATGGACAGCCACCCCAGCTACACAGA TACCCCAGTGAGTGCCCCACGGACTCTGAGTGCAGTGGGGACCCCCCTCAATGCCCTGGGCTCTCCATAT CGAGTCATCACCTCTGCCATGGGCCCACCCTCAGGAGCACTTGCAGCGCCTCCAGGAATCAACTTGGTTG CCCCACCCAGCTCTCAGCTAAATGTGGTCAACAGTGTCAGCAGTTCAGAGGACATCAAGCCCTTACCAGG GCTTCCCGGGATTGGAAACATGAACTACCCATCCACCAGCCCCGGATCTCTGGTTAAACACATCTGTGCC ATCTGTGGAGACAGATCCTCAGGAAAGCACTACGGGGTATACAGTTGTGAAGGCTGCAAAGGGTTCTTCA AGAGGACGATAAGGAAGGACCTCATCTACACGTGTCGGGATAATAAAGACTGCCTCATTGACAAGCGTCA GCGCAACCGCTGCCAGTACTGTCGCTATCAGAAGTGCCTTGTCATGGGCATGAAGAGGGAAGCTGTGCAA GAAGAAAGACAGAGGAGCCGAGAGCGAGCTGAGAGTGAGGCAGAATGTGCTACCAGTGGTCATGAAGACA TGCCTGTGGAGAGGATTCTAGAAGCTGAACTTGCTGTTGAACCAAAGACAGAATCCTATGGTGACATGAA TATGGAGAACTCGACAAATGACCCTGTTACCAACATATGTCATGCTGCTGACAAGCAGCTTTTCACCCTC GTTGAATGGGCCAAGCGTATTCCCCACTTCTCTGACCTCACCTTGGAGGACCAGGTCATTTTGCTTCGGG CAGGGTGGAATGAATTGCTGATTGCCTCTTTCTCCCACCGCTCAGTTTCCGTGCAGGATGGCATCCTTCT GGCCACGGGTTTACATGTCCACCGGAGCAGTGCCCACAGTGCTGGGGTCGGCTCCATCTTTGACAGAGTC CTAACTGAGCTGGTTTCCAAAATGAAAGACATGCAGATGGACAAGTCGGAACTGGGATGCCTGCGAGCCA TTGTACTCTTTAACCCAGATGCCAAGGGCCTGTCCAACCCCTCTGAGGTGGAGACTCTGCGAGAGAAGGT TTATGCCACCCTTGAGGCCTACACCAAGCAGAAGTATCCGGAACAGCCAGGCAGGTTTGCCAAGCTGCTG CTGCGCCTCCCAGCTCTGCGTTCCATTGGCTTGAAATGCCTGGAGCACCTCTTCTTCTTCAAGCTCATCG GGGACACCCCCATTGACACCTTCCTCATGGAGATGTTGGAGACCCCGCTGCAGATCACC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC204093 protein sequence
Red=Cloning site Green=Tags(s) MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPY RVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICA ICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQ EERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTL VEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRV LTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLL LRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_006917 |
| ORF Size | 1389 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_006917.5 |
| RefSeq Size | 2205 bp |
| RefSeq ORF | 1392 bp |
| Locus ID | 6258 |
| UniProt ID | P48443 |
| Domains | HOLI, zf-C4 |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| Protein Pathways | Adipocytokine signaling pathway, Non-small cell lung cancer, Pathways in cancer, PPAR signaling pathway, Small cell lung cancer, Thyroid cancer |
| MW | 50.9 kDa |
| Gene Summary | This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010] |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Docosahexaenoic acid (DHA), a nutritional supplement, modulates steroid insensitivity in asthma
,Panda, L;Gheware, A;Jaiswal, A;Saha, D;Desiraju, B;Rehman, R;Ray, A;Dutta, J;Singh, S;Yadav, M;Sowpati, D;Chattopadhyay, S;SubbaRao, M;Mahesh, P;Prakash, Y;Chowdhury, S;Agrawal, A;Ghosh, B;Mabalirajan, U;,
bioRxiv
[Retinoid X Receptor gamma]
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Receptor-binding affinities of bisphenol A and its next-generation analogs for human nuclear receptors
,Liu, X;Sakai, H;Nishigori, M;Suyama, K;Nawaji, T;Ikeda, S;Nishigouchi, M;Okada, H;Matsushima, A;Nose, T;Shimohigashi, M;Shimohigashi, Y;,
Toxicol. Appl. Pharmacol.
,PubMed ID 31195007
[Retinoid X Receptor gamma]
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Cocaine Induces Nuclear Export and Degradation of Neuronal Retinoid X Receptor-? via a TNF-a/JNK- Mediated Mechanism
,Kovalevich, J;Yen, W;Ozdemir, A;Langford, D;,
J Neuroimmune Pharmacol
,PubMed ID 25586717
[Retinoid X Receptor gamma]
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CNX-013-B2, a unique pan tissue acting rexinoid, modulates several nuclear receptors and controls multiple risk factors of the metabolic syndrome without risk of hypertriglyceridemia, hepatomegaly and body weight gain in animal models
,Sadasivuni, MK;Reddy, BM;Singh, J;Anup, MO;Sunil, V;Lakshmi, MN;Yogeshwari, S;Chacko, SK;Pooja, TL;Dandu, A;Harish, C;Gopala, AS;Pratibha, S;Naveenkumar, BS;Pallavi, PM;Verma, MK;Moolemath, Y;Somesh, BP;Venkataranganna, MV;Jagannath, MR;,
Diabetol Metab Syndr
,PubMed ID 25143786
[Retinoid X Receptor gamma]
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Documents
| Product Manuals |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204093L1 | Lenti ORF clone of Human retinoid X receptor, gamma (RXRG), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204093L2 | Lenti ORF clone of Human retinoid X receptor, gamma (RXRG), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC204093L3 | Lenti ORF clone of Human retinoid X receptor, gamma (RXRG), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204093L4 | Lenti ORF clone of Human retinoid X receptor, gamma (RXRG), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG204093 | RXRG (tGFP-tagged) - Human retinoid X receptor, gamma (RXRG), transcript variant 1 |
CNY 4,370.00 |
|
| SC319914 | RXRG (untagged)-Human retinoid X receptor, gamma (RXRG), transcript variant 1 |
CNY 3,656.00 |
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