p27 KIP 1 (CDKN1B) (NM_004064) Human 3' UTR Clone

Specifications

Product Data
Product Name	p27 KIP 1 (CDKN1B) (NM_004064) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CDKN4; KIP1; MEN1B; MEN4; P27KIP1
ACCN	NM_004064
Insert Size	1372 bp
Sequence Data	Insert Sequence (showhide) >SC214055 3’UTR clone of NM_004064 The sequence shown below is from the reference sequence of NM_004064. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGCCTGGCCTCAGAAGACGTCAAACGTAAACAGCTCGAATTAAGAATATGTTTCCTTGTTTATCAGAT ACATCACTGCTTGATGAAGCAAGGAAGATATACATGAAAATTTTAAAAATACATATCGCTGACTTCATG GAATGGACATCCTGTATAAGCACTGAAAAACAACAACACAATAACACTAAAATTTTAGGCACTCTTAAA TGATCTGCCTCTAAAAGCGTTGGATGTAGCATTATGCAATTAGGTTTTTCCTTATTTGCTTCATTGTAC TACCTGTGTATATAGTTTTTACCTTTTATGTAGCACATAAACTTTGGGGAAGGGAGGGCAGGGTGGGGC TGAGGAACTGACGTGGAGCGGGGTATGAAGAGCTTGCTTTGATTTACAGCAAGTAGATAAATATTTGAC TTGCATGAAGAGAAGCAATTTTGGGGAAGGGTTTGAATTGTTTTCTTTAAAGATGTAATGTCCCTTTCA GAGACAGCTGATACTTCATTTAAAAAAATCACAAAAATTTGAACACTGGCTAAAGATAATTGCTATTTA TTTTTACAAGAAGTTTATTCTCATTTGGGAGATCTGGTGATCTCCCAAGCTATCTAAAGTTTGTTAGAT AGCTGCATGTGGCTTTTTTAAAAAAGCAACAGAAACCTATCCTCACTGCCCTCCCCAGTCTCTCTTAAA GTTGGAATTTACCAGTTAATTACTCAGCAGAATGGTGATCACTCCAGGTAGTTTGGGGCAAAAATCCGA GGTGCTTGGGAGTTTTGAATGTTAAGAATTGACCATCTGCTTTTATTAAATTTGTTGACAAAATTTTCT CATTTTCTTTTCACTTCGGGCTGTGTAAACACAGTCAAAATAATTCTAAATCCCTCGATATTTTTAAAG ATCTGTAAGTAACTTCACATTAAAAAATGAAATATTTTTTAATTTAAAGCTTACTCTGTCCATTTATCC ACAGGAAAGTGTTATTTTTCAAGGAAGGTTCATGTAGAGAAAAGCACACTTGTAGGATAAGTGAAATGG ATACTACATCTTTAAACAGTATTTCATTGCCTGTGTATGGAAAAACCATTTGAAGTGTACCTGTGTACA TAACTCTGTAAAAACACTGAAAAATTATACTAACTTATTTATGTTAAAAGATTTTTTTTAATCTAGACA ATATACAAGCCAAAGTGGCATGTTTTGTGCATTTGTAAATGCTGTGTTGGGTAGAATAGGTTTTCCCCT CTTTTGTTAAATAATATGGCTATGCTTAAAAGGTTGCATACTGAGCCAAGTATAATTTTTTGTAATGTG TGAAAAAGATGCCAATTATTGTTACACATTAAGTAATCAATAAAGAAAACTTCCATAGCTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004064.5
Synonyms	CDKN4; KIP1; MEN1B; MEN4; P27KIP1
Summary	This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
Locus ID	1027
MW	52.8

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