CD44 Mouse Monoclonal Antibody [Clone ID: CVS18]

Specifications

Product Data
Clone Name	CVS18
Applications	FC
Recommend Dilution	Flow cytometry: Neat, use 10µl to label 106 cells in 100µl.
Reactivity	Equine
Host	Mouse
Clonality	Monoclonal
Immunogen	Equine leucocytes
Specificity	Clone CVS18 antibody detects equine CD44 and may be used as a pan equine leucocyte marker.
Formulation	0.09% Sodium azide, 1% BSA and 5% Sucrose Label: PE State: Purified State: Lyophilised purified IgG Label: R. Phycoerythrin
Reconstitution Method	Restore with 1.0 ml distilled water.
Purification	Affinity chromatography on Protein G
Conjugation	PE
Storage Condition	Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Database Link	UniProt ID Q05078
Background	CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.
Synonyms	LHR, MDU2, MDU3, MIC4, CDw44, Epican, ECMR-III, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, PGP-1
Reference Data

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