BLK Mouse Monoclonal Antibody [Clone ID: 1E6]

Specifications

Product Data
Clone Name	1E6
Applications	ELISA, FC, IF, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow Cytometry: 1/200 - 1/400.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human BLK expressed in E. Coli.
Specificity	Recognizes BLK
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	58 kDa
Gene Name	BLK proto-oncogene, Src family tyrosine kinase
Database Link	Entrez Gene 640 Human UniProt ID P51451
Background	Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development . Activation of B cells by various ligands is accompanied by activation of Blk . It has been suggested that Blk is involved in the control of B cell differentiation and proliferation . Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis . Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response .
Synonyms	B lymphocyte kinase, p55-BLK, p55BLK
Reference Data

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