Uroplakin II (UPK2) (NM_006760) Human Mass Spec Standard

Specifications

Product Data
Description	UPK2 MS Standard C13 and N15-labeled recombinant protein (NP_006751)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC223168
Predicted MW	19.4 kDa
Protein Sequence	Sequence Link (showhide) >RC223168 protein sequence Red=Cloning site Green=Tags(s) MAPLLPIRTLPLILILLALLSPGAADFNISSLSGLLSPALTESLLVALPPCHLTGGNATLMVRRANDSKV VTSSFVVPPCRGRRELVSVVDSGAGFTVTRLSAYQVTNLVPGTKFYISYLVKKGTATESSREIPMSTLPR RNMESIGLGMARTGGMVVITVLLSVAMFLLVLGFIIALALGSRK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006751
RefSeq Size	947
RefSeq ORF	552
Synonyms	UP2; UPII
Locus ID	7379
Cytogenetics	11q23.3
Summary	This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009]
Protein Families	Transmembrane

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