LY6H (NM_002347) Human Mass Spec Standard

Specifications

Product Data
Description	LY6H MS Standard C13 and N15-labeled recombinant protein (NP_002338)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205136
Predicted MW	14.7 kDa
Protein Sequence	Sequence Link (showhide) >RC205136 protein sequence Red=Cloning site Green=Tags(s) MLPAAMKGLGLALLAVLLCSAPAHGLWCQDCTLTTNSSHCTPKQCQPSDTVCASVRITDPSSSRKDHSVN KMCASSCDFVKRHFFSDYLMGFINSGILKVDVDCCEKDLCNGAAGAGHSPWALAGGLLLSLGPALLWAGP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002338
RefSeq Size	950
RefSeq ORF	420
Synonyms	NMLY6
Locus ID	4062
Cytogenetics	8q24.3
Summary	Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.[UniProtKB/Swiss-Prot Function]

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