Mouse Cd300a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cd300a
Locus ID	217303
Kit Components	GA213453G1, Cd300a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213453G2, Cd300a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213453G3, Cd300a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001347654, NM_170758, NM_001359812
Synonyms	B230315M08Rik; Clm8; LMIR1; MAIR-I; MAIR-Ia; mcpir1; MMAC8; Pigr4
Summary	Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed:12874256, PubMed:12893283, PubMed:16339535). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 (By similarity).[UniProtKB/Swiss-Prot Function]

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