Mouse Myzap activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Myzap
Locus ID	102371
Kit Components	GA211701G1, Myzap gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211701G2, Myzap gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211701G3, Myzap gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033208
Synonyms	AA407270; AV006038; Gcom1; Gm640; Grinl1a7; Myozap
Summary	Plays a role in cellular signaling via Rho-related GTP-binding proteins and activation of transcription factor SRF. Targets TJP1 to cell junctions (By similarity). In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 (By similarity).[UniProtKB/Swiss-Prot Function]

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