Mouse Kdm4c activation kit by CRISPRa
CAT#: GA210620
Kdm4c CRISPRa kit - CRISPR gene activation of mouse lysine (K)-specific demethylase 4C
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Kdm4c |
Locus ID | 76804 |
Kit Components | GA210620G1, Kdm4c gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210620G2, Kdm4c gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210620G3, Kdm4c gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001172095, NM_144787, NM_001356561 |
Synonyms | 2410141F18Rik; AA517467; Gasc1; Jmjd2c |
Summary | Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN508736 | Kdm4c - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |