Mouse Rnf115 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rnf115
Locus ID	67845
Kit Components	GA207541G1, Rnf115 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207541G2, Rnf115 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207541G3, Rnf115 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_026406
Synonyms	2610028E05Rik; AU042696; Zfp364
Summary	E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys-48'- and/or 'Lys-63'-linked polyubiquitination of substrates and may play a role in diverse biological processes. Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4.[UniProtKB/Swiss-Prot Function]

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