Mouse Faap20 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Faap20
Locus ID	67513
Kit Components	GA207373G1, Faap20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207373G2, Faap20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207373G3, Faap20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033134, NM_001190445, NM_001347262, NR_033802
Synonyms	RP23-298E4.5
Summary	Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1 (By similarity).[UniProtKB/Swiss-Prot Function]

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