Mouse Brd3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Brd3
Locus ID	67382
Kit Components	GA207296G1, Brd3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207296G2, Brd3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207296G3, Brd3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001113573, NM_001113574, NM_023336
Synonyms	2410084F24Rik; AW060456; Fsrg2; ORFX; RINGL3
Summary	Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors (PubMed:21536911). Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets (PubMed:21536911).[UniProtKB/Swiss-Prot Function]

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