Mouse Mapk8ip2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mapk8ip2
Locus ID	60597
Kit Components	GA206407G1, Mapk8ip2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206407G2, Mapk8ip2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206407G3, Mapk8ip2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_021921
Synonyms	3230402N03Rik; AI847694; AW049958; IB2; Jip2; R75148
Summary	The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells (By similarity).[UniProtKB/Swiss-Prot Function]

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