Mouse Ppp2r3c activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ppp2r3c
Locus ID	59032
Kit Components	GA206345G1, Ppp2r3c gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206345G2, Ppp2r3c gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206345G3, Ppp2r3c gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_021529
Synonyms	4930511A21Rik; 5730412A08Rik; G4-1; G5pr
Summary	May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.[UniProtKB/Swiss-Prot Function]

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