Mouse Sit1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sit1
Locus ID	54390
Kit Components	GA205696G1, Sit1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205696G2, Sit1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205696G3, Sit1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_019436
Synonyms	Sit
Summary	Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.[UniProtKB/Swiss-Prot Function]

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