Mouse Slc25a1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc25a1
Locus ID	13358
Kit Components	GA201067G1, Slc25a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201067G2, Slc25a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201067G3, Slc25a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_153150
Synonyms	1300019P08Rik; 2610100G11Rik; AI194714; Ctp; Dgsj; Slc20a3
Summary	Citrate transporter that mediates the exchange of mitochondrial citrate for cytosolic malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis- but not trans-aconitate and to a lesser extend maleate and succinate. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. Required for proper neuromuscular junction formation.[UniProtKB/Swiss-Prot Function]

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