Human C6orf138 (PTCHD4) activation kit by CRISPRa
CAT#: GA118543
PTCHD4 CRISPRa kit - CRISPR gene activation of human patched domain containing 4
CNY 12,255.00
CNY 9,296.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | PTCHD4 |
Locus ID | 442213 |
Kit Components | GA118543G1, C6orf138 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118543G2, C6orf138 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118543G3, C6orf138 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001013732, NM_207499 |
Synonyms | C6orf138; dJ402H5.2; PTCH53 |
Summary | Could act as a repressor of canonical hedgehog signaling by antagonizing the effects of SMO, as suggested by down-regulation of hedgehog target genes, including GLI1, PTCH1, and PTCH2 in PTCHD4-expressing cells.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN418697 | PTCHD4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |