Human Synaptotagmin VI (SYT6) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SYT6
Locus ID	148281
Kit Components	GA115667G1, Synaptotagmin VI gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115667G2, Synaptotagmin VI gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115667G3, Synaptotagmin VI gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001253772, NM_001270805, NM_205848, NR_045589, N50928, NM_001366224, NM_001366223, NM_001366225, NM_001366226
Summary	The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011]

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