Human FRMPD2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FRMPD2
Locus ID	143162
Kit Components	GA115449G1, FRMPD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115449G2, FRMPD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115449G3, FRMPD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001017929, NM_001018071, NM_001042512, NM_001318191, NM_152428, NR_033178
Synonyms	FERM and PDZ domain containing 2; MGC35285; MGC87776; MGC87777; MGC90186; PDZD5C; PDZ domain containing 5C; PDZK5C
Summary	This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2009]

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