Human LYPD6B activation kit by CRISPRa
CAT#: GA115120
LYPD6B CRISPRa kit - CRISPR gene activation of human LY6/PLAUR domain containing 6B
CNY 12,255.00
CNY 2,400.00
CNY 3,705.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | LYPD6B |
Locus ID | 130576 |
Kit Components | GA115120G1, LYPD6B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115120G2, LYPD6B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115120G3, LYPD6B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001317002, NM_001317003, NM_001317004, NM_001317005, NM_001317006, NM_177964 |
Synonyms | CT116; LYPD7 |
Summary | Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2):alpha-5:beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN407249 | LYPD6B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |