Human Coiled Coil Domain Containing Protein 3 (CCDC3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CCDC3
Locus ID	83643
Kit Components	GA113223G1, Coiled Coil Domain Containing Protein 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113223G2, Coiled Coil Domain Containing Protein 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113223G3, Coiled Coil Domain Containing Protein 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001282658, NM_031455
Synonyms	RP11-347I22.1
Summary	Negatively regulates TNF-alpha-induced pro-inflammatory response in endothelial cells (ECs) via inhibition of TNF-alpha-induced NF-kappaB activation in ECs (PubMed:25193116). Positively regulates lipid accumulation in adipose cells (By similarity).[UniProtKB/Swiss-Prot Function]

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