Human MTA3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MTA3
Locus ID	57504
Kit Components	GA111542G1, MTA3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111542G2, MTA3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111542G3, MTA3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001282755, NM_001282756, NM_001330442, NM_001330443, NM_001330444, NM_020744
Summary	Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.[UniProtKB/Swiss-Prot Function]

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