Human Reticulocalbin 3 (RCN3) activation kit by CRISPRa

CAT#: GA111466

RCN3 CRISPRa kit - CRISPR gene activation of human reticulocalbin 3



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
Rabbit Polyclonal Anti-RCN3 Antibody
    • 100 ul

CNY 5,250.00


RCN3 (Myc-DDK-tagged)-Human reticulocalbin 3, EF-hand calcium binding domain (RCN3)
    • 10 ug

CNY 2,400.00
CNY 3,990.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol RCN3
Locus ID 57333
Kit Components

GA111466G1, Reticulocalbin 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111466G2, Reticulocalbin 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111466G3, Reticulocalbin 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_020650
Synonyms RLP49
Summary Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (PubMed:16433634, PubMed:28939891). Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3 (By similarity). By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis (By similarity). Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (PubMed:28939891). This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (PubMed:16433634).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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