Human ST6GALNAC1 activation kit by CRISPRa
CAT#: GA110986
ST6GALNAC1 CRISPRa kit - CRISPR gene activation of human ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | ST6GALNAC1 |
Locus ID | 55808 |
Kit Components | GA110986G1, ST6GALNAC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110986G2, ST6GALNAC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110986G3, ST6GALNAC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001289107, NM_018414, NR_110309 |
Synonyms | HSY11339; SIAT7A; ST6GalNAcI; STYI |
Summary | Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM, Mar 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN416697 | ST6GALNAC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
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