Human PPPDE1 (DESI2) activation kit by CRISPRa

CAT#: GA109512

DESI2 CRISPRa kit - CRISPR gene activation of human desumoylating isopeptidase 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
Rabbit Polyclonal Anti-DESI2 Antibody
    • 100 ul

CNY 5,250.00


DESI2 (Myc-DDK-tagged)-Human PPPDE peptidase domain containing 1 (PPPDE1)
    • 10 ug

CNY 2,400.00
CNY 3,705.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol DESI2
Locus ID 51029
Kit Components

GA109512G1, PPPDE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109512G2, PPPDE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109512G3, PPPDE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001297746, NM_016076, NR_123735, NR_123736
Synonyms C1orf121; CGI-146; DESI; DeSI-2; DESI1; FAM152A; PNAS-4; PPPDE1
Summary Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization (PubMed:28483520).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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