Human PHAPI2 / APRIL (ANP32B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ANP32B
Locus ID	10541
Kit Components	GA107205G1, PHAPI2 / APRIL gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107205G2, PHAPI2 / APRIL gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107205G3, PHAPI2 / APRIL gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_006401
Synonyms	APRIL; PHAPI2; SSP29
Summary	Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.[UniProtKB/Swiss-Prot Function]

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