Human SEC24D activation kit by CRISPRa
CAT#: GA106661
SEC24D CRISPRa kit - CRISPR gene activation of human SEC24 homolog D, COPII coat complex component
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | SEC24D |
Locus ID | 9871 |
Kit Components | GA106661G1, SEC24D gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106661G2, SEC24D gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106661G3, SEC24D gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001318066, NM_014822 |
Synonyms | CLCRP2 |
Summary | The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN407747 | SEC24D - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |