Human USP6NL activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	USP6NL
Locus ID	9712
Kit Components	GA106522G1, USP6NL gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106522G2, USP6NL gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106522G3, USP6NL gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001080491, NM_014688, NR_125732
Synonyms	RNTRE; TRE2NL; USP6NL-IT1
Summary	Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.[UniProtKB/Swiss-Prot Function]

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